Calcium
Also known as: calcium citrate, calcium carbonate
Recommended Dosage
500–1000 mg
Essential for bone health, but food sources preferred. If supplementing, always pair with Vitamin D3 and K2.
Evidence Rating: Grade A — Strong Evidence
Multiple high-quality RCTs, systematic reviews, or meta-analyses with consistent findings.
Forms Comparison
Calcium Citrate
✓ High AbsorptionBetter absorbed than carbonate. Can be taken with or without food. Preferred form.
Calcium Carbonate
~ Moderate AbsorptionCheapest and most common form. Must be taken with food for adequate absorption. Contains most elemental calcium per pill.
Calcium Hydroxyapatite (MCHC)
✓ High AbsorptionDerived from bone. Contains additional bone-building minerals. Most expensive.
Interaction Warnings
Inhibits iron absorption — take at different times
Reduces levothyroxine absorption
Take separately by 30+ minutes
⚠️ Important Notes
- Get from food first if possible
- Always combine with Vitamin D3 and K2
- Excess supplementation linked to cardiovascular concerns
Clinical Evidence (1 study)
Calcium intake and bone mineral density
Tai V et al. (2015) — BMJ
Supplementation modestly increases BMD at all sites
View on PubMedRelated Supplements
Zinc
Grade A — Strong EvidenceEssential mineral for immune function, wound healing, and testosterone production. Lozenges reduce cold duration by ~33%.
Magnesium Glycinate
Grade A — Strong EvidenceHighly bioavailable form of magnesium. Strong evidence for sleep quality, muscle relaxation, and stress reduction. Most adults are deficient.
Vitamin D3
Grade A — Strong EvidenceEssential hormone precursor. Most people in northern latitudes are deficient. Strong evidence for immunity, bone health, and mood.
Boron
Grade C — PreliminaryTrace mineral that supports calcium metabolism, vitamin D utilization, and potentially testosterone levels.
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⚕️ Important Disclaimer
This information is for educational purposes only. It is not medical advice. Always consult a healthcare provider before starting any supplement regimen, especially if you take medications or have health conditions.
Evidence Stack does not sell supplements and has no affiliate relationships with supplement manufacturers.