Cordyceps

Also known as: Cordyceps sinensis, Cordyceps militaris, caterpillar fungus, CS-4

Grade B — Moderate Evidencemushroomperformanceenergy

Recommended Dosage

10004000 mg

Morning or pre-workout. With or without food.

Medicinal mushroom with RCT evidence for improved VO2 max and exercise tolerance. 3-4g/day for athletic performance.

Last reviewed: 2026-03-09

Evidence Rating: Grade B — Moderate Evidence

Some RCTs with positive results, or strong observational evidence. More research may refine our understanding.

Interaction Warnings

ImmunosuppressantsModerate

May antagonize immunosuppressive drugs; caution post-transplant

Blood thinnersLow

Possible mild antiplatelet; monitor warfarin

Diabetes medicationsLow

May lower blood sugar; monitor

⚠️ Important Notes

  • Avoid raw powder without extraction (poor bioavailability)
  • Caution in autoimmune disease

Clinical Evidence (2 studies)

Cordyceps CS-4 improved VO2 max in elderly

Chen S et al. (2010) — J Altern Complement Med

Improved VO2 max and ventilatory threshold; RCT

View on PubMed

Cordyceps militaris improved VO2 max and time to exhaustion

Hirsch KR et al. (2017) — J Diet Suppl

4g improved VO2 max and time to exhaustion; randomized trial

View on PubMed

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