Holy Basil (Tulsi)

Also known as: Ocimum sanctum, Ocimum tenuiflorum, tulsi, sacred basil

Grade B — Moderate Evidenceherbadaptogen

Recommended Dosage

300–600 mg

With meals. Consistent daily use for adaptogenic effects.

Ayurvedic adaptogen with evidence for stress reduction and blood glucose stabilization. Gentle daily-use herb.

🧘Stress & Anxiety🛡️Immunity
Last reviewed: 2026-03-09

Evidence Rating: Grade B — Moderate Evidence

Some RCTs with positive results, or strong observational evidence. More research may refine our understanding.

Interaction Warnings

Antidiabetic medicationsModerate

Blood glucose lowering; may potentiate insulin or metformin

WarfarinLow

Mild antiplatelet/anticoagulant from eugenol; monitor at high doses

Thyroid medicationsLow

May interact with thyroid hormone metabolism

⚠️ Important Notes

  • Avoid therapeutic doses in pregnancy (uterine stimulant)
  • May have anti-fertility effect (animal data)
  • Very safe at culinary doses

Clinical Evidence (2 studies)

Tulsi extract reduced stress and anxiety

Bhattacharyya D et al. (2008) — J Clin Diagn Res

Significantly reduced stress and anxiety in healthy adults; RCT

View on PubMed

Tulsi: comprehensive review of evidence

Cohen MM (2014) — J Ayurveda Integr Med

Comprehensive review of adaptogenic, cognitive, metabolic, and immunological evidence

View on PubMed

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Ashwagandha

Grade A — Strong Evidence

Ayurvedic adaptogen with strong clinical evidence for cortisol reduction (15-30%), stress relief, and exercise performance.

Rhodiola Rosea

Grade B — Moderate Evidence

Adaptogenic herb with strong evidence for reducing stress-related fatigue. Comparable to low-dose antidepressants for mild depression.

Schisandra

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⚕️ Important Disclaimer

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