Hawthorn

Also known as: Crataegus monogyna, Crataegus laevigata, WS 1442 extract

Grade B — Moderate Evidenceherbheart

Recommended Dosage

160–1800 mg WS 1442

With meals, twice daily. Effects require weeks to months.

Cochrane-reviewed for heart failure (NYHA I-II): improves exercise tolerance and symptoms. Modest blood pressure reduction.

❤️Heart Health
Last reviewed: 2026-03-09

Evidence Rating: Grade B — Moderate Evidence

Some RCTs with positive results, or strong observational evidence. More research may refine our understanding.

Interaction Warnings

DigoxinModerate

May potentiate cardiac effects; monitor levels and ECG

PDE5 inhibitors (sildenafil)Moderate

Additive vasodilation; possible hypotension

AntihypertensivesLow

Additive BP-lowering; monitor

⚠️ Important Notes

  • WS 1442 (18.75% oligomeric procyanidins) is the best-studied form
  • Consistent long-term use needed
  • Avoid in pregnancy

Clinical Evidence (2 studies)

Hawthorn for heart failure: Cochrane review

Pittler MH et al. (2003) — Cochrane Database Syst Rev

Systematic review of 8 RCTs: improved exercise tolerance and symptom reduction

View on PubMed

SPICE trial: hawthorn in heart failure

Holubarsch CJ et al. (2008) — Eur J Heart Fail

900mg/day in mild-moderate heart failure; large prospective study

View on PubMed

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⚕️ Important Disclaimer

This information is for educational purposes only. It is not medical advice. Always consult a healthcare provider before starting any supplement regimen, especially if you take medications or have health conditions.

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